SUGT1P4-STRA6LP-CCDC180

Chr 9

SUGT1P4-STRA6LP-CCDC180 readthrough

Also known as: LOC100499484-C9ORF174

This locus produces read-through transcripts that span a pseudogene and protein-coding sequence but are candidates for nonsense-mediated decay and do not express functional protein. No disease associations have been established for this locus, as the transcripts are not expected to produce a stable protein product.

ResearchSummary from RefSeq
Clinical SummarySUGT1P4-STRA6LP-CCDC180
📋
ClinVar Variants
15 unique Pathogenic / Likely Pathogenic· 236 VUS of 296 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

296 submitted variants in ClinVar

Classification Summary

Pathogenic15
VUS236
Likely Benign32
Benign2
Conflicting6
15
Pathogenic
236
VUS
32
Likely Benign
2
Benign
6
Conflicting

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
15
0
15
Likely Pathogenic
0
0
0
0
0
VUS
0
232
4
0
236
Likely Benign
0
23
1
8
32
Benign
0
2
0
0
2
Conflicting
6
Total0257208291

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

SUGT1P4-STRA6LP-CCDC180 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
Open Research Assistant →

No publications found for SUGT1P4-STRA6LP-CCDC180