STAG3L5P-PVRIG2P-PILRB

Chr 7

STAG3L5P-PVRIG2P-PILRB readthrough

Also known as: LOC101735302-LOC101752334-PILRB

This locus represents naturally occurring readthrough transcription among the neighboring LOC101735302 (stromal antigen 3 pseudogene), LOC101752334 (poliovirus receptor related immunoglobulin domain containing pseudogene) and PILRB (paired immunoglobin-like type 2 receptor beta) genes on chromosome 7. The readthrough transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Jun 2013]

52
ClinVar variants
6
Pathogenic / LP
pLI score
0
Active trials
Clinical SummarySTAG3L5P-PVRIG2P-PILRB
📋
ClinVar Variants
6 Pathogenic / Likely Pathogenic· 41 VUS of 52 total submissions
Some data sources returned errors (1)

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

52 submitted variants in ClinVar

Classification Summary

Pathogenic6
VUS41
Likely Benign5
6
Pathogenic
41
VUS
5
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
6
0
6
Likely Pathogenic
0
0
0
0
0
VUS
0
40
1
0
41
Likely Benign
0
4
1
0
5
Benign
0
0
0
0
0
Total0448052

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

STAG3L5P-PVRIG2P-PILRB · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.