SPDYE15

Chr 7

speedy/RINGO cell cycle regulator family member E15

Also known as: SPDYE15P

Predicted to enable protein kinase binding activity. [provided by Alliance of Genome Resources, Jul 2025]

14
ClinVar variants
12
Pathogenic / LP
pLI score
0
Active trials
Clinical SummarySPDYE15
📋
ClinVar Variants
12 Pathogenic / Likely Pathogenic· 1 VUS of 14 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

14 submitted variants in ClinVar

Classification Summary

Pathogenic11
Likely Pathogenic1
VUS1
Likely Benign1
11
Pathogenic
1
Likely Pathogenic
1
VUS
1
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
11
Likely Pathogenic
1
VUS
1
Likely Benign
1
Benign
0
Total14

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

SPDYE15 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.