SOCS3-DT

Chr 17

SOCS3 divergent transcript

NCBI Gene: 101928674ENSG00000266970
0
Active trials
4
Pathogenic / LP
6
ClinVar variants
0
Pubs (1 yr)
—
Missense Z
—
LOEUF
Clinical Summary— SOCS3-DT
📋
ClinVar Variants
4 Pathogenic / Likely Pathogenic· 1 VUS of 6 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

6 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic3
Likely Pathogenic1
VUS1
Likely Benign1
3
Pathogenic
1
Likely Pathogenic
1
VUS
1
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————3
Likely Pathogenic
————1
VUS
————1
Likely Benign
————1
Benign
————0
Total—6

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

SOCS3-DT · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients