SNORA62

Chr 21

small nucleolar RNA, H/ACA box 62

Also known as: E2, E2-1, RNE2, RNU108

SNORA62 encodes a small nucleolar RNA that is part of the box H/ACA ribonucleoprotein complex involved in RNA processing and pseudouridylation of ribosomal RNA. Mutations cause intellectual disability with developmental delay and dysmorphic features, inherited in an autosomal recessive pattern. The phenotype typically presents in early childhood with global developmental delays affecting multiple systems.

OMIMResearchSummary from RefSeq

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

SNORA62 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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