SNHG8

Chr 4

small nucleolar RNA host gene 8

Also known as: LINC00060, NCRNA00060

SNHG8 encodes a small nucleolar RNA host gene predicted to be involved in RNA processing within the nucleolus. Currently, no established human diseases have been definitively associated with mutations in this gene. The clinical significance of SNHG8 variants in pediatric neurological conditions remains to be determined.

Summary from RefSeq
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0
Active trials
7
Pubs (1 yr)
19
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummarySNHG8
📋
ClinVar Variants
19 unique Pathogenic / Likely Pathogenic· 2 VUS of 25 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

25 submitted variants in ClinVar

Classification Summary

Pathogenic18
Likely Pathogenic1
VUS2
Likely Benign2
18
Pathogenic
1
Likely Pathogenic
2
VUS
2
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
18
Likely Pathogenic
1
VUS
2
Likely Benign
2
Benign
0
Total23

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

SNHG8 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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