SNHG7
Chr 9small nucleolar RNA host gene 7
Also known as: NCRNA00061
Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Clinical Summary— SNHG7
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ClinVar Variants
71 Pathogenic / Likely Pathogenic· 7 VUS of 81 total submissions
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
81 submitted variants in ClinVar
Classification Summary
Pathogenic68
Likely Pathogenic3
VUS7
Benign1
Conflicting2
68
Pathogenic
3
Likely Pathogenic
7
VUS
1
Benign
2
Conflicting
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 68 |
Likely Pathogenic | — | — | — | — | 3 |
VUS | — | — | — | — | 7 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 1 |
Conflicting | — | 2 | |||
| Total | — | 81 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
SNHG7 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
Long non-coding RNA SNHG7 serves as a diagnostic biomarker for acute coronary syndrome and its predictive value for the clinical outcome after percutaneous coronary intervention
Liao R et al.·J Cardiothorac Surg
2024
LncRNA SNHG7 promotes non-small cell lung cancer progression and cisplatin resistance by inducing autophagic activity
She K et al.·J Thorac Dis
2023
Analysis of PANoptosis-Related LncRNA-miRNA-mRNA Network Reveals LncRNA SNHG7 Involved in Chemo-Resistance in Colon Adenocarcinoma
Huang J et al.·Front Oncol
2022
Long Noncoding RNA SNHG7 Is a Diagnostic and Prognostic Marker for Colon Adenocarcinoma
Jiang C et al.·Front Oncol
2022
Top 5 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
Clinicopathological and prognostic value of long noncoding RNA SNHG7 in cancers: a meta-analysis and bioinformatics.
Wang J et al.·Aging (Albany NY)
2021Meta-analysis
Prognostic effect of lncRNA SNHG7 on cancer outcome: a meta and bioinformatic analysis.
Zhang Y et al.·BMC Cancer
2022Review
The Prognostic Value of Long Non-Coding RNA SNHG7 in Human Cancer: A Meta-Analysis.
Yu K et al.·Curr Pharm Biotechnol
2022Meta-analysis
Is Long Noncoding SNHG7 a Reliable Diagnostic Tool for Metastasis Diagnosis of Cancer: A Meta-Analysis.
Hu M et al.·Genet Test Mol Biomarkers
2021Meta-analysis
LncRNA SNHG7 Serves as a Potential Biomarker on the Prognosis of Human Solid Tumors: A Meta-Analysis.
Yi P et al.·Curr Pharm Biotechnol
2021Meta-analysis
Top 5 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Identification of a potential target for autoimmune hepatitis: SNHG7.
Pang X et al.·Medicine (Baltimore)
2025Open Access
Long non-coding RNA SNHG7 as a key driver of colorectal cancer proliferation and metastasis by inhibiting cuproptosis.
Guo X et al.·Eur J Med Res
2025Open Access
LncRNA SNHG7/miR-181b-5p/TLR4 Activates Inflammation And Promotes Pyroptosis Through NF-κB Signaling in Diabetic Nephropathy.
Zhang M et al.·Inflammation
2025Open Access
LncRNA SNHG7 inhibits apoptosis and proliferation of osteoarthritis cells induced by IL-β through sponging miR-146b.
Lin N et al.·Connect Tissue Res
2025
Abnormal Expression of lncRNA SNHG7 in Dry Eye Disease and Its Effect on Human Conjunctival Epithelial Cells.
Liu S et al.·Tohoku J Exp Med
2025
Top 5 resultsSearch Europe PMC ↗
External Resources
Links to major genomics databases and tools