SNHG5
Chr 6small nucleolar RNA host gene 5
Also known as: C6orf160, LINC00044, NCRNA00044, U50HG
This gene produces a long non-coding RNA that regulates gene expression by sequestering microRNAs and stabilizing mRNAs through interaction with RNA-binding proteins. Currently, no established pediatric neurological diseases have been definitively linked to mutations in this gene. Clinical significance in neurogenetics remains to be determined.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
33 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 15 |
Likely Pathogenic | — | — | — | — | 1 |
VUS | — | — | — | — | 6 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 0 |
| Total | — | 22 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
SNHG5 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools