SNHG29

Chr 17

small nucleolar RNA host gene 29

Also known as: ACIL, C17orf45, C17orf76-AS1, FAM211A-AS1, LRRC75A-AS1, NCRNA00188, TSAP19

SNHG29 encodes a small nucleolar RNA host gene predicted to be involved in RNA processing within the nucleolus. Currently, no established human diseases have been definitively linked to mutations in this gene. The clinical significance and inheritance pattern remain to be determined as pathogenic variants have not been well-characterized.

ResearchSummary from RefSeq
Clinical SummarySNHG29
📋
ClinVar Variants
16 unique Pathogenic / Likely Pathogenic· 38 VUS of 67 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

67 submitted variants in ClinVar

Classification Summary

Pathogenic16
VUS38
Likely Benign10
Benign1
16
Pathogenic
38
VUS
10
Likely Benign
1
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
16
0
16
Likely Pathogenic
0
0
0
0
0
VUS
0
37
1
0
38
Likely Benign
1
8
0
1
10
Benign
0
1
0
0
1
Total14617165

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

SNHG29 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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