SMC2-DT
Chr 9SMC2 divergent transcript
Also known as: SMC2-AS1
I cannot write a clinical summary for SMC2-DT based on the provided information. No data about the protein function, associated diseases, inheritance patterns, or pathogenic mechanisms was included in your request. To create an accurate clinical summary following your specifications, I would need specific information about what SMC2-DT encodes, what conditions result from its mutations, and how those mutations cause disease.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
22 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 19 |
Likely Pathogenic | — | — | — | — | 0 |
VUS | — | — | — | — | 3 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 0 |
| Total | — | 22 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
SMC2-DT · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools