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SLC9D1

Chr 13

solute carrier family 9 member D1

Also known as: C13orf11, TMCO3

This gene encodes a sodium/hydrogen or potassium/hydrogen antiporter that facilitates membrane translocation and activation of AKT1 upon IGF1-dependent phosphorylation. Mutations cause cornea guttata with anterior polar cataract, a rare inherited vision defect affecting the cornea and lens. The inheritance pattern for this condition has not been established.

OMIMResearchSummary from RefSeq, UniProt
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/SLC9D1?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

SLC9D1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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No publications found for SLC9D1