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SCAR26
Chr 19ARX-ray repair cross complementing 1
Also known as: RCC, SCAR26
The protein encoded by this gene repairs DNA single-strand breaks by interacting with DNA ligase III, polymerase beta, and poly(ADP-ribose) polymerase in the base excision repair pathway. Mutations cause autosomal recessive spinocerebellar ataxia (SCAR26), affecting the cerebellum and associated motor coordination systems. The inheritance pattern is autosomal recessive.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/SCAR26?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
SCAR26 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools