RRAGC-DT

Chr 1

RRAGC divergent transcript

Also known as: LENGA

NCBI Gene: 105378663ENSG00000228436

I cannot provide a clinical summary for RRAGC-DT as no information about this gene's protein function, associated diseases, or inheritance pattern was provided in the data below the instructions.

Research
Clinical Summary— RRAGC-DT
📋
ClinVar Variants
3 unique Pathogenic / Likely Pathogenic· 78 VUS of 90 total submissions
Explore recent and relevant literature in Research Assistant →

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

90 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic2
Likely Pathogenic1
VUS78
Likely Benign3
Benign2
2
Pathogenic
1
Likely Pathogenic
78
VUS
3
Likely Benign
2
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
2
0
2
Likely Pathogenic
0
0
1
0
1
VUS
0
78
0
0
78
Likely Benign
0
1
1
1
3
Benign
0
2
0
0
2
Total0814186

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

RRAGC-DT · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients