RNU5B-1
Chr 15RNA, U5B small nuclear 1
Also known as: NEDSJL, RNU5B, RNU5B-1P, U5B1
Predicted to be involved in formation of quadruple SL/U4/U5/U6 snRNP and spliceosomal tri-snRNP complex assembly. Predicted to be part of U4/U6 x U5 tri-snRNP complex and U5 snRNP. [provided by Alliance of Genome Resources, Jul 2025]
ResearchGenerating clinical summary…
Clinical highlights
Gene–disease validity (ClinGen)
Some data sources returned errors (1)
omim: Error: OMIM fetch failed: 429
ReNU syndrome & the snRNA disorders — features, recurrent variants, where they sit, testing and counsellingOverview →
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Trials that enrol by condition rarely name the gene: RNU5B- related neurodevelopmental disorder with seizures and joint laxity
External Resources
Links to major genomics databases and tools