RB1-DT
Chr 13RB1 divergent transcript
Also known as: LINC00441, ncRNA-RB1
I cannot provide a clinical gene summary for RB1-DT as no functional or phenotypic information has been provided in the data below this prompt. Without information about the protein function, associated diseases, inheritance patterns, or clinical features, it would not be appropriate to write a clinical summary that could be used by child neurologists for patient care decisions.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
65 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | 0 | 0 | 33 | 0 | 33 |
Likely Pathogenic | 0 | 0 | 1 | 0 | 1 |
VUS | 0 | 0 | 27 | 0 | 27 |
Likely Benign | 0 | 0 | 0 | 0 | 0 |
Benign | 0 | 0 | 1 | 0 | 1 |
Conflicting | — | 3 | |||
| Total | 0 | 0 | 62 | 0 | 65 |
LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
RB1-DT · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools