PWRN2
Chr 15Prader-Willi region non-protein coding RNA 2
Also known as: NCRNA00199
Clinical Summary— PWRN2
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
PWRN2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Clinical Literature
Open Research Assistant →Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
LncRNAs upregulated in insulin resistance are downregulated by metformin in a liver cell line.
Tello-Flores VA et al.·Cell Mol Biol (Noisy-le-grand)
2025
Mosaicism for a 15q11.2 microduplication with a normal euploid cell line at amniocentesis in a pregnancy with a favorable fetal outcome and postnatal decrease of the aneuploid cell line with the microduplication.
Chen CP et al.·Taiwan J Obstet Gynecol
2023
Novel role of lncRNAs regulatory network in papillary thyroid cancer
Su Y et al.·Biochem Biophys Rep
2024
Influence of Long Non-Coding RNAs on Human Oocyte Development
Wang L et al.·Pharmgenomics Pers Med
2024
Long non-coding RNAs: novel players in the pathogenesis of polycystic ovary syndrome
Tu M et al.·Ann Transl Med
2021
Top 5 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
Potential of Long Non-Coding RNAs in Age-Related Macular Degeneration.
Blasiak J et al.·Int J Mol Sci
2021Review
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
LncRNA PWRN2 promotes polycystic ovary syndrome progression via epigenetically reducing ATRX by recruiting LSD1.
Gong Z et al.·Reprod Biol
2023
Sulforaphane alleviates LPS-induced inflammatory injury in ARPE-19 cells by repressing the PWRN2/NF-kB pathway.
Song H et al.·Immunopharmacol Immunotoxicol
2022
Long non-coding RNA PWRN2 regulates cytotoxicity in an in vitro model of age-related macular degeneration.
Yu X et al.·Biochem Biophys Res Commun
2021Functional
LncRNA PWRN2 stimulates the proliferation and migration in papillary thyroid carcinoma through the miR-325/DDX5 axis.
Xin CH et al.·Eur Rev Med Pharmacol Sci
2020
Construction and analysis of a lncRNA (PWRN2)-mediated ceRNA network reveal its potential roles in oocyte nuclear maturation of patients with PCOS.
Huang X et al.·Reprod Biol Endocrinol
2018Open AccessCohort
Top 5 resultsSearch Europe PMC ↗
External Resources
Links to major genomics databases and tools