PWAR5

Chr 15

Prader Willi/Angelman region RNA 5

Also known as: D15S226E, PAR-5, PAR5

Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Jul 2025]

313
ClinVar variants
306
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryPWAR5
📋
ClinVar Variants
306 Pathogenic / Likely Pathogenic· 6 VUS of 313 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

313 submitted variants in ClinVar

Classification Summary

Pathogenic297
Likely Pathogenic9
VUS6
Likely Benign1
297
Pathogenic
9
Likely Pathogenic
6
VUS
1
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
297
Likely Pathogenic
9
VUS
6
Likely Benign
1
Benign
0
Total313

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

PWAR5 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →