PTCSC2
Chr 9papillary thyroid carcinoma susceptibility candidate 2
Clinical Summary— PTCSC2
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
PTCSC2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
The Effect of LL37 Antimicrobial Peptide on FOXE1 and lncRNA PTCSC 2 Genes Expression in Colorectal Cancer (CRC) and Normal Cells
Al-Darraji MN et al.·Asian Pac J Cancer Prev
2022
Novel Susceptibility Genes Drive Familial Non-Medullary Thyroid Cancer in a Large Consanguineous Kindred
Majdalani P et al.·Int J Mol Sci
2023
Constructing a Ferroptosis-related Long Non-coding RNA Signature to Predict the Prognostic of Head and Neck Squamous Cell Carcinoma Patients by Bioinformatic Analysis
Lu R et al.·Biochem Genet
2022Cohort
Prognostic significance of an autophagy-related long non-coding RNA signature in patients with oral and oropharyngeal squamous cell carcinoma
Jiang Q et al.·Oncol Lett
2021Cohort
The Contribution of Genetic Variants to the Risk of Papillary Thyroid Carcinoma in the Kazakh Population: Study of Common Single Nucleotide Polymorphisms and Their Clinicopathological Correlations
Mussazhanova Z et al.·Front Endocrinol (Lausanne)
2021
Top 5 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2.
He H et al.·J Clin Endocrinol Metab
2015
Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.
He H et al.·Proc Natl Acad Sci U S A
2015Functional
Risk genetic polymorphism and haplotype associated with papillary thyroid cancer and their relation to associated diseases in Slovak population.
Duffek M et al.·Bratisl Lek Listy
2022
Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters.
Jendrzejewski J et al.·Thyroid
2016
Top 5 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Variants in TPO rs2048722, PTCSC2 rs925489 and SEMA4G rs4919510 affect thyroid carcinoma susceptibility risk.
Shen Z et al.·BMC Med Genomics
2023Open Access
Suggestive evidence of the genetic association of TMOD1 and PTCSC2 polymorphisms with thyroid carcinoma in the Chinese Han population.
Tong K et al.·BMC Endocr Disord
2022Open Access
MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus.
Wang Y et al.·Proc Natl Acad Sci U S A
2017
Top 5 resultsSearch Europe PMC ↗
External Resources
Links to major genomics databases and tools