PSORS1C3

Chr 6

psoriasis susceptibility 1 candidate 3

Also known as: NCRNA00196

NCBI Gene: 100130889ENSG00000204528
1
ClinVar variants
1
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— PSORS1C3
📋
ClinVar Variants
1 Pathogenic / Likely Pathogenic of 1 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

1 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic1
1
Pathogenic

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————1
Likely Pathogenic
————0
VUS
————0
Likely Benign
————0
Benign
————0
Total—1

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

PSORS1C3 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

OMIM
Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC
Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical Response to Anti-IL-12/IL-23 Treatment of Patients with Psoriasis.
Morelli M et al.·Vaccines (Basel)
2022🔓 Open AccessCohort
Association of PSORS1C3, CARD14 and TLR4 genotypes and haplotypes with psoriasis susceptibility.
Linh NTT et al.·Genet Mol Biol
2022🔓 Open Access
Construction of a multiple-class classifier based on mRNAs and lncRNA FAM66A and PSORS1C3 for predicting distant metastasis in lung adenocarcinoma.
Lin GY et al.·Ann Transl Med
2022🔓 Open Access
lncRNA PSORS1C3 is regulated by glucocorticoids and fine-tunes OCT4 expression in non-pluripotent cells.
Mirzadeh Azad F et al.·Sci Rep
2019🔓 Open Access
HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis.
Wiśniewski A et al.·Mol Genet Genomics
2018🔓 Open Access
Top 5 resultsSearch Europe PMC ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools