PINX1-DT

Chr 8

PINX1 divergent transcript

NCBI Gene: 101929229ENSG00000253695
0
Active trials
55
Pathogenic / LP
58
ClinVar variants
1
Pubs (1 yr)
—
Missense Z
—
LOEUF
Clinical Summary— PINX1-DT
📋
ClinVar Variants
55 Pathogenic / Likely Pathogenic· 3 VUS of 58 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

58 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic54
Likely Pathogenic1
VUS3
54
Pathogenic
1
Likely Pathogenic
3
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————54
Likely Pathogenic
————1
VUS
————3
Likely Benign
————0
Benign
————0
Total—58

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

PINX1-DT · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 5 full-text resultsSearch PubTator3 ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Top 5 resultsSearch Europe PMC ↗

External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients