PDCD2
Chr 6programmed cell death 2
Also known as: RP8, ZMYND7
This protein functions as a chaperone for ribosomal protein uS5, cotranslationally associating with uS5 and accompanying it to ribosomal assembly sites in the nucleus. The gene is not highly constrained against loss-of-function variants and currently lacks established disease associations in OMIM, though it appears to function redundantly with PDCD2L in ribosomal protein chaperoning.
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Highly tolerant — LoF variants common in population
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
PDCD2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools