PCAT7

Chr 9

prostate cancer associated transcript 7

I cannot provide a clinical summary for PCAT7 as no information about this gene's protein function, associated diseases, or inheritance pattern has been provided in the data below the instructions. The gene appears to be a pseudogene or long non-coding RNA (based on the "PCAT" prefix typically indicating "Prostate Cancer Associated Transcript"), but without specific functional and clinical data, I cannot create an accurate clinical summary following the strict rules provided.

Clinical SummaryPCAT7
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ClinVar Variants
14 unique Pathogenic / Likely Pathogenic· 33 VUS of 58 total submissions
Some data sources returned errors (1)

ncbi: Error: NCBI fetch failed: 429 https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

58 submitted variants in ClinVar

Classification Summary

Pathogenic14
VUS33
Likely Benign2
Benign4
14
Pathogenic
33
VUS
2
Likely Benign
4
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
14
0
14
Likely Pathogenic
0
0
0
0
0
VUS
0
32
1
0
33
Likely Benign
0
1
0
1
2
Benign
1
2
0
1
4
Total13515253

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

PCAT7 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC