PANDAR

Chr 6

promoter of CDKN1A antisense DNA damage activated RNA

Also known as: PANDA

This gene produces a non-coding RNA that is thought to regulate the response to DNA damage. This gene is induced by tumor protein p53 and interacts with and modulates the activity of a transcription factor that induce pro-apoptotic genes. Deregulation of this gene is associated with cancer progression. [provided by RefSeq, Dec 2017]

1
ClinVar variants
1
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryPANDAR
📋
ClinVar Variants
1 Pathogenic / Likely Pathogenic of 1 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

1 submitted variants in ClinVar

Classification Summary

Pathogenic1
1
Pathogenic

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
1
Likely Pathogenic
0
VUS
0
Likely Benign
0
Benign
0
Total1

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

PANDAR · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Long non-coding RNAs in retinoblastoma.
Yang M et al.·Pathol Res Pract
2019Review
Top 10 resultsSearch PubMed ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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