NRXN1-DT
Chr 2NRXN1 divergent transcript
I cannot write a clinical gene summary for NRXN1-DT because no information about this gene's protein function, associated diseases, or inheritance pattern was provided in your message. To create an accurate clinical summary following your strict guidelines, I would need data about what the protein does, what conditions result from mutations, and the inheritance pattern.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
32 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 26 |
Likely Pathogenic | — | — | — | — | 2 |
VUS | — | — | — | — | 1 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 1 |
| Total | — | 30 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
NRXN1-DT · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools