NPIPA3

Chr 16

nuclear pore complex interacting protein family member A3

NCBI Gene: 642778ENSG00000224712UniProt: F8WFD2
40
ClinVar variants
28
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— NPIPA3
📋
ClinVar Variants
28 Pathogenic / Likely Pathogenic· 12 VUS of 40 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

40 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic22
Likely Pathogenic6
VUS12
22
Pathogenic
6
Likely Pathogenic
12
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————22
Likely Pathogenic
————6
VUS
————12
Likely Benign
————0
Benign
————0
Total—40

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

NPIPA3 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

OMIM

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence

No publications found for NPIPA3

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools