NOA3

Chr 22

origin of replication NOA3

This region contains an origin of DNA replication. This sequence can promote replication of a plasmid, and is also a site of initiation of nascent strand synthesis in its native genomic context. [provided by RefSeq, Feb 2016]

6
ClinVar variants
6
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryNOA3
📋
ClinVar Variants
6 Pathogenic / Likely Pathogenic of 6 total submissions
Some data sources returned errors (3)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/NOA3?content-type=application/json&expand=1

gnomad: Error: Gene not found

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

6 submitted variants in ClinVar

Classification Summary

Pathogenic6
6
Pathogenic

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
6
Likely Pathogenic
0
VUS
0
Likely Benign
0
Benign
0
Total6

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

NOA3 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →