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NEDAMSS

Chr 14AD

interferon regulatory factor 2 binding protein like

Also known as: C14orf4, EAP1, NEDAMSS

This gene encodes a transcription factor that regulates female reproductive function. Mutations cause neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures, inherited in an autosomal dominant pattern. The condition involves multiple neurological systems with a regressive course affecting motor function, communication, and seizure control.

GeneReviewsOMIMResearchSummary from RefSeq, OMIM
AD1 OMIM phenotype
📖
GeneReview available — NEDAMSS
Authoritative clinical overview · Recommended first read
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Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/NEDAMSS?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

NEDAMSS · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC