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NEDAHM

Chr 1AR

small vasohibin binding protein

Also known as: CCDC23, NEDAHM, SPG94

The NEDAHM protein enables microtubule binding and peptidase activator activity, and is involved in axon development and regulation of metallopeptidase activity. Mutations cause neurodevelopmental disorder with ataxia, hypotonia, and microcephaly, inherited in an autosomal recessive pattern. This disorder affects the central nervous system with prominent motor and developmental features.

OMIMResearchSummary from RefSeq, OMIM
AR1 OMIM phenotype
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/NEDAHM?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

NEDAHM · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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No publications found for NEDAHM