NBAT1

Chr 6

neuroblastoma associated transcript 1

Also known as: CASC14, NBAT-1

NCBI Gene: 729177ENSG00000260455
3
ClinVar variants
3
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— NBAT1
📋
ClinVar Variants
3 Pathogenic / Likely Pathogenic of 3 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

3 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic3
3
Pathogenic

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————3
Likely Pathogenic
————0
VUS
————0
Likely Benign
————0
Benign
————0
Total—3

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

NBAT1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

OMIM
Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Long Non-coding RNAs and their Role in Metastasis.
Weidle UH et al.·Cancer Genomics Proteomics
2017Review
NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2.
Hu P et al.·Oncotarget
2015
A negative feedback loop between long noncoding RNA NBAT1 and Sox9 inhibits the malignant progression of gastric cancer cells.
Yan J et al.·Biosci Rep
2018
Long noncoding RNA NBAT1 suppresses hepatocellular carcinoma progression via competitively associating with IGF2BP1 and decreasing c-Myc expression.
Wei L et al.·Hum Cell
2021
Long noncoding RNA neuroblastoma-associated transcript 1 gene inhibits malignant cellular phenotypes of bladder cancer through miR-21/SOCS6 axis.
Liu Z et al.·Cell Death Dis
2018
Expression of long noncoding RNA NBAT1 is associated with the outcome of patients with non-small cell lung cancer.
Wang DL et al.·Rev Assoc Med Bras (1992)
2020Cohort
Lnc NBAT1 Inhibits the Proliferation and Migration of Liver Cancer Cells Through the miR-21/PDCD4/AP-1 Signaling Axis.
Zai H et al.·Appl Biochem Biotechnol
2025
Expression level and clinical significance of NBAT-1 in human cancers: a systematic review and meta-analysis.
Yu Y et al.·BMC Cancer
2024Meta-analysis
Serum lncRNAs, NBAT-1, and FOXCUT signature in hepatocellular carcinoma developed on top of chronic hepatitis C.
Ali MA et al.·Mol Carcinog
2023
The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation.
Pandey GK et al.·Cancer Cell
2014
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC
Top 5 resultsSearch Europe PMC ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools