MYCNOS
Chr 2MYCN opposite strand
Also known as: MYCN-AS1, N-CYM, NCYM, NYCM
This gene encodes a small protein that stabilizes the MYCN oncogene by inhibiting GSK3B-mediated phosphorylation and may also function as a regulatory RNA that recruits transcriptional regulators to promote MYCN expression. MYCNOS is primarily associated with neuroblastoma, a pediatric cancer typically presenting in infancy and early childhood. The inheritance pattern and role in Mendelian neurological disorders remains unclear, as this gene is best characterized in the context of somatic cancer biology.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
MYCNOS · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools