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MRXSRC
Chr XXLDCl-/H+ antiporter 4
Also known as: CLC4, ClC-4, ClC-4A, MRX15, MRX49, MRXSRC
CLCN4 encodes chloride channel 4, a voltage-dependent chloride channel whose physiological role remains unknown but may contribute to neuronal function. Mutations cause Raynaud-Claes syndrome, an X-linked dominant neurodevelopmental disorder. This gene is located on the X chromosome at band p22.3 and demonstrates evolutionary conservation with a CpG island.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/MRXSRC?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
MRXSRC · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools