MROH7-TTC4

Chr 1

MROH7-TTC4 readthrough (NMD candidate)

Also known as: HEATR8-TTC4

NCBI Gene: 100527960ENSG00000271723

This locus represents a read-through transcript between neighboring genes MROH7 and TTC4 that undergoes alternative splicing to produce multiple variants targeted for nonsense-mediated decay and is unlikely to produce functional protein products. No disease associations have been established for this read-through transcript based on the available information.

ResearchSummary from RefSeq
Clinical Summary— MROH7-TTC4
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Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

ClinVar

Protein Context — Lollipop Plot

MROH7-TTC4 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

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External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients