MORN1

Chr 1

MORN repeat containing 1

ResearchGenerating clinical summary…
0
Active trials
2
Pubs (1 yr)
P/LP submissions
P/LP missense
1.12
LOEUF
GOF
Mechanism· predicted
Some data sources returned errors (1)

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

gnomAD v4 — loss-of-function & missense intolerance

Tolerant — LoF & missense variants common in population
LoF Constraint?
1.12LOEUF
pLI 0.000
Z-score 1.10
OE 0.77 (0.541.12)
Tolerant

Highly tolerant — LoF variants common in population

Missense Constraint?
-0.28Z-score
OE missense 1.05 (0.951.15)
308 obs / 294.2 exp
Tolerant

Tolerant to missense variation

Observed / Expected Ratios?
LoF OE?0.77 (0.541.12)
00.351.4
Missense OE?1.05 (0.951.15)
00.61.4
Synonymous OE?1.00
01.21.6
LoF obs/exp: 20 / 26.0Missense obs/exp: 308 / 294.2Syn Z: -0.04

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

MORN1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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