MFF-DT
Chr 2MFF divergent transcript
I cannot provide a clinical summary for MFF-DT as no functional, phenotypic, or inheritance information has been provided in the data below. Without specific information about what this gene encodes, associated diseases, or inheritance patterns, I cannot write an accurate clinical summary following the strict rules requiring only supported claims.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
300 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | 10 | 2 | 0 | 0 | 12 |
Likely Pathogenic | 33 | 88 | 2 | 0 | 123 |
VUS | 1 | 85 | 8 | 2 | 96 |
Likely Benign | 0 | 1 | 23 | 10 | 34 |
Benign | 0 | 0 | 1 | 1 | 2 |
Conflicting | — | 3 | |||
| Total | 44 | 176 | 34 | 13 | 270 |
LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
MFF-DT · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools