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MERRF
myoclonic epilepsy and ragged red muscle fibers
I cannot write a clinical gene summary for "MERRF" because MERRF (Myoclonic Epilepsy with Ragged Red Fibers) is a mitochondrial syndrome caused by mutations in various mitochondrial genes, most commonly MT-TK (mitochondrial tRNA lysine), rather than a single nuclear gene. To provide an accurate summary, I would need specific information about which mitochondrial gene causes MERRF that you're referring to, along with the protein function and inheritance data for that particular gene.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/MERRF?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
MERRF · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools