Ensembl is currently experiencing issues
The Ensembl REST API is temporarily unavailable. Some gene data (transcript details, protein domains) may be incomplete. Other data sources are unaffected.
You can check Ensembl's status at status.ensembl.org
MCOPS2
Chr XXLDBCL6 corepressor
Also known as: ANOP2, MAA2, MCOPS2
The protein encoded by this gene is a transcriptional corepressor that selectively interacts with the POZ domain of BCL6 and recruits histone deacetylases to regulate gene expression. Mutations cause syndromic microphthalmia with X-linked dominant inheritance. This condition primarily affects eye development but may involve additional organ systems as part of the syndromic presentation.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/MCOPS2?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
MCOPS2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No open access results found
External Resources
Links to major genomics databases and tools