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MCLMR
Chr 10ADkinesin family member 11
Also known as: EG5, HKSP, KNSL1, MCLMR, TRIP5
The protein is a kinesin-like motor protein that functions in spindle dynamics, chromosome positioning, centrosome separation, and establishing bipolar spindles during mitosis. Mutations cause microcephaly with or without chorioretinopathy, lymphedema, or impaired intellectual development with autosomal dominant inheritance. This condition affects brain development and can involve the eyes and lymphatic system.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/MCLMR?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
MCLMR · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools