LSINCT5

Chr 5

long stress-induced non-coding transcript 5

NCBI Gene: 101234261ENSG00000281560
55
ClinVar variants
54
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— LSINCT5
📋
ClinVar Variants
54 Pathogenic / Likely Pathogenic· 1 VUS of 55 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

55 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic54
VUS1
54
Pathogenic
1
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————54
Likely Pathogenic
————0
VUS
————1
Likely Benign
————0
Benign
————0
Total—55

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

LSINCT5 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

OMIM
Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
LSINCT5: A Novel lncRNA in Cancers.
Qiu X et al.·Curr Med Chem
2023Review
LSINCT5 predicts unfavorable prognosis and exerts oncogenic function in osteosarcoma.
He W et al.·Biosci Rep
2019
Long noncoding RNA LSINCT5 is upregulated and promotes the progression of esophageal squamous cell carcinoma.
Jing L et al.·Eur Rev Med Pharmacol Sci
2019
Emerging circulating MiRNAs and LncRNAs in upper gastrointestinal cancers.
Abdi E et al.·Expert Rev Mol Diagn
2020Review
Long non-coding RNA LSINCT5 predicts negative prognosis and exhibits oncogenic activity in gastric cancer.
Xu MD et al.·Medicine (Baltimore)
2014
Increased B-type-natriuretic peptide promotes myocardial cell apoptosis via the B-type-natriuretic peptide/long non-coding RNA LSINCT5/caspase-1/interleukin 1β signaling pathway.
Zhang X et al.·Mol Med Rep
2015
Circulating CUDR, LSINCT-5 and PTENP1 long noncoding RNAs in sera distinguish patients with gastric cancer from healthy controls.
Dong L et al.·Int J Cancer
2015Cohort
[SIGNIFICANCE OF NONCODING RNA IN BREAST CANCER].
Sato F·Nihon Geka Gakkai Zasshi
2015
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC
Top 5 resultsSearch Europe PMC ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools