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LROMI1

Chr 17

lncRNA regulator of macrophage immunity 1

NCBI Gene: 107985080

I cannot provide a clinical gene summary for LROMI1 as no information about this gene's protein function, associated diseases, or inheritance pattern was provided in the data you referenced. To write an accurate clinical summary following the specified guidelines, I would need details about what the LROMI1 protein does, what neurological conditions result from mutations in this gene, and how the condition is inherited.

Research
Clinical Summary— LROMI1
📋
ClinVar Variants
42 unique Pathogenic / Likely Pathogenic of 42 total submissions
Explore recent and relevant literature in Research Assistant →
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/LROMI1?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

42 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic38
Likely Pathogenic4
38
Pathogenic
4
Likely Pathogenic

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————38
Likely Pathogenic
————4
VUS
————0
Likely Benign
————0
Benign
————0
Total—42

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

LROMI1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →

No publications found for LROMI1

External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients