LNCARSR
Chr 9lncRNA regulator of Akt signaling associated with HCC and RCC
Also known as: lnc-TALC
Clinical Summary— LNCARSR
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ClinVar Variants
15 Pathogenic / Likely Pathogenic· 1 VUS of 16 total submissions
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
16 submitted variants in ClinVar
Classification Summary
Pathogenic15
VUS1
15
Pathogenic
1
VUS
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 15 |
Likely Pathogenic | — | — | — | — | 0 |
VUS | — | — | — | — | 1 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 0 |
| Total | — | 16 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
LNCARSR · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
Correction: Long noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progression
Shen P et al.·Cell Death Dis
2021
The novel hydrogen-PT2385-silncARSR nanocomplex impairs tumor angiogenesis and mitochondrial activity in sunitinib-resistant renal cancer.
Hu S et al.·Mater Today Bio
2025
Correction to: Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway
Chi Y et al.·J Transl Med
2021
Emerging long noncoding RNA polymorphisms as novel predictors of survival in cancer.
Abdi E et al.·Pathol Res Pract
2022
Top 4 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
Long noncoding RNA ARSR is associated with a poor prognosis in patients with colorectal cancer.
Li T et al.·J Gene Med
2020Cohort
LncARSR sponges miR-129-5p to promote proliferation and metastasis of bladder cancer cells through increasing SOX4 expression.
Liao C et al.·Int J Biol Sci
2020
Long noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progression.
Shen P et al.·Cell Death Dis
2020
Roles of LncRNA ARSR in tumor proliferation, drug resistance, and lipid and cholesterol metabolism.
Li Z et al.·Clin Transl Oncol
2025Review
Top 5 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
METTL3-induced lncARSR aggravates neuroblastoma tumorigenic properties through stabilizing PHOX2B.
Meng X et al.·Pathol Res Pract
2024
LncARSR promotes glioma tumor growth by mediating glycolysis through the STAT3/HK2 axis.
Tian Z et al.·Cytokine
2024
The lncARSR/PTEN/Akt/nuclear factor-kappa B feedback regulatory loop contributes to doxorubicin resistance in hepatocellular carcinoma.
Li Y et al.·J Biochem Mol Toxicol
2022
Renal cell carcinoma-derived exosomes deliver lncARSR to induce macrophage polarization and promote tumor progression via STAT3 pathway.
Zhang W et al.·Int J Biol Sci
2022Open Access
[Balectin-3 affects the stability of vulnerable coronary atherosclerosis plaques by targeted modulation of lncARSR].
Xu M et al.·Nan Fang Yi Ke Da Xue Xue Bao
2021
Top 5 resultsSearch Europe PMC ↗
External Resources
Links to major genomics databases and tools