LINP1

Chr 10

lncRNA in non-homologous end joining pathway 1

Also known as: LINC00707, PARROT

I cannot write a clinical summary for LINP1 because no information about this gene's protein function, associated diseases, or inheritance patterns has been provided in the data below the gene name. To create an accurate clinical summary following the specified guidelines, I would need details about what the LINP1 protein does, what conditions result from mutations in this gene, and the inheritance pattern of associated disorders.

Clinical SummaryLINP1
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ClinVar Variants
12 unique Pathogenic / Likely Pathogenic· 2 VUS of 16 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

16 submitted variants in ClinVar

Classification Summary

Pathogenic11
Likely Pathogenic1
VUS2
Benign2
11
Pathogenic
1
Likely Pathogenic
2
VUS
2
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
11
Likely Pathogenic
1
VUS
2
Likely Benign
0
Benign
2
Total16

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

LINP1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Key Publications
Landmark & review papers · by relevance
PubMed
Top 4 results · since 2015Search PubMed ↗