LINC02210-CRHR1

Chr 17

LINC02210-CRHR1 readthrough

Also known as: CRHR1-IT1-CRHR1, MGC57346-CRHR1

This locus represents naturally occurring readthrough transcription between neighboring genes CRHR1-IT1, CRHR1 intronic transcript 1 (Gene ID: 147081) and CRHR1, corticotropin releasing hormone receptor 1 (Gene ID: 1394) on chromosome 17. The readthrough transcript encodes a protein that shares sequence identity with the product of the CRHR1 gene. [provided by RefSeq, Dec 2016]

Research

ResearchGenerating clinical summary…

Clinical Summary— LINC02210-CRHR1

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ClinVar Variants

49 VUS of 67 total submissions

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Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

67 submitted variants in ClinVar

ClinVar

Classification Summary

VUS49

Likely Benign8

Benign6

VUS

Likely Benign

Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

Classification	Missense + Inframe	Non-coding	Synonymous	Total
Pathogenic	0	0	0	0
Likely Pathogenic	0	0	0	0
VUS	49	0	0	49
Likely Benign	6	0	2	8
Benign	2	2	2	6
Total	57	2	4	63

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

33 pathogenic / likely-pathogenic (of 36) ClinVar copy-number / structural variants overlap LINC02210-CRHR1 — these span large chromosomal regions, not the gene specifically, and are excluded from the counts above. Explore in CNV tools →