LASTR

Chr 10

lncRNA associated with SART3 regulation of splicing

Also known as: LINC02657

I don't see any information provided about the LASTR gene below your request. To write an accurate clinical summary following your strict rules about using only the provided information, I would need details about the protein function, associated diseases, inheritance pattern, and any relevant clinical context for this gene. Could you please provide the gene information that should accompany this request?

Clinical SummaryLASTR
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ClinVar Variants
14 unique Pathogenic / Likely Pathogenic· 2 VUS of 18 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

18 submitted variants in ClinVar

Classification Summary

Pathogenic12
Likely Pathogenic2
VUS2
Likely Benign1
Benign1
12
Pathogenic
2
Likely Pathogenic
2
VUS
1
Likely Benign
1
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
12
Likely Pathogenic
2
VUS
2
Likely Benign
1
Benign
1
Total18

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

LASTR · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
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