LARP4B-DT

Chr 10

LARP4B divergent transcript

I cannot provide a clinical gene summary for LARP4B-DT as no functional, disease association, or inheritance pattern information has been provided in the data you've shared. LARP4B-DT appears to be a transcript designation rather than a protein-coding gene, and without supporting clinical or functional data, I cannot make any claims about its role in pediatric neurological conditions.

Clinical SummaryLARP4B-DT
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ClinVar Variants
15 unique Pathogenic / Likely Pathogenic· 3 VUS of 19 total submissions
Some data sources returned errors (1)

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Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

19 submitted variants in ClinVar

Classification Summary

Pathogenic13
Likely Pathogenic2
VUS3
Likely Benign1
13
Pathogenic
2
Likely Pathogenic
3
VUS
1
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
13
Likely Pathogenic
2
VUS
3
Likely Benign
1
Benign
0
Total19

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

LARP4B-DT · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
Open Research Assistant →

No publications found for LARP4B-DT