LAP3
Chr 4leucine aminopeptidase 3
Also known as: HEL-S-106, LAP, LAPEP, PEPS
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Typical tolerance to LoF variation
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
LAP3 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIM
NOT YET RECRUITINGTissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)
NOT YET RECRUITINGU69-CART-Cells For R/R T-ALL
RECRUITINGBiomoleculars Markers of Sensitivity to Pre- and Post-operative Chemotherapy of Gastric and Cardia Adenocarcinomas: a Pilot Study
RECRUITINGIbrutinib Followed by BR (Bendamustine and Rituximab) as a Time-Limited Therapy for Waldenström Macroglobulinemia
NOT YET RECRUITINGDecitabine in Treating Patients With Myelofibrosis
ACTIVE NOT RECRUITINGMotixafortide for MRD Sensitization in AML
RECRUITINGGenetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response
ACTIVE NOT RECRUITINGRelevance of [68Ga]Ga -PentixaFor-PET for Initial Staging and Therapeutic Evaluation of Multiple Myeloma
ACTIVE NOT RECRUITINGPrognostic Analyses on a Validation Series of Patients With Waldenström's Disease
RECRUITINGNew Preclinical and Clinical Approaches to Mesothelioma
RECRUITINGPrognostic Value of Circulating Tumoral DNA After the First 6 Months of Treatment in Patients With Waldenström Macroglobulinemia
RECRUITINGExternal Resources
Links to major genomics databases and tools