IGLV2-33

Chr 22

immunoglobulin lambda variable 2-33 (non-functional)

Also known as: IGLV233, V1-9

Predicted to be involved in immune response. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Jul 2025]

26
ClinVar variants
23
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryIGLV2-33
📋
ClinVar Variants
23 Pathogenic / Likely Pathogenic· 2 VUS of 26 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

26 submitted variants in ClinVar

Classification Summary

Pathogenic23
VUS2
Benign1
23
Pathogenic
2
VUS
1
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
23
Likely Pathogenic
0
VUS
2
Likely Benign
0
Benign
1
Total26

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

IGLV2-33 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence

No publications found for IGLV2-33

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →