IFI44

Chr 1

interferon induced protein 44

Also known as: MTAP44, TLDC5, p44

NCBI Gene: 10561 ENSG00000137965 UniProt: Q8TCB0 OMIM: 610468

The IFI44 protein aggregates to form microtubular structures and is predicted to be involved in cellular immune responses to viral and bacterial infections. This gene is not constrained against loss-of-function variants (LOEUF 1.496), and no established Mendelian diseases have been definitively linked to IFI44 mutations in the current literature.

OMIM ResearchSummary from RefSeq, UniProt

Predicted to be involved in immune response. Predicted to act upstream of or within cellular response to virus and response to bacterium. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

OMIM ResearchGenerating clinical summary…

Active trials

Pubs (1 yr)

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P/LP submissions

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P/LP missense

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LOEUF

Mechanism· predicted

Some data sources returned errors (1)

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