HOXA10-HOXA9
Chr 7HOXA10-HOXA9 readthrough
Also known as: HDSP
This locus represents naturally occurring read-through transcription between the neighboring HOXA10 (homeobox A10) and HOXA9 (full description written out) genes on chromosome 7. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Mar 2011]
Some data sources returned errors (1)
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
163 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | 0 | 0 | 9 | 0 | 9 |
Likely Pathogenic | 0 | 0 | 0 | 0 | 0 |
VUS | 0 | 141 | 1 | 0 | 142 |
Likely Benign | 0 | 0 | 1 | 5 | 6 |
Benign | 0 | 1 | 1 | 4 | 6 |
| Total | 0 | 142 | 12 | 9 | 163 |
LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly
View in ClinVar →HOXA10-HOXA9 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools