GSTT4

Chr 22

glutathione S-transferase theta 4

Also known as: GSTTP1, HS322B1A

Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

48
ClinVar variants
14
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryGSTT4
📋
ClinVar Variants
14 Pathogenic / Likely Pathogenic· 28 VUS of 48 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

48 submitted variants in ClinVar

Classification Summary

Pathogenic11
Likely Pathogenic3
VUS28
Likely Benign3
Benign1
Conflicting2
11
Pathogenic
3
Likely Pathogenic
28
VUS
3
Likely Benign
1
Benign
2
Conflicting

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
11
Likely Pathogenic
3
VUS
28
Likely Benign
3
Benign
1
Conflicting
2
Total48

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

GSTT4 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →