FAM85B

Chr 8

family with sequence similarity 85 member B

Also known as: lncRNA-HEIM

NCBI Gene: 105379219ENSG00000253893
0
Active trials
40
Pathogenic / LP
93
ClinVar variants
0
Pubs (1 yr)
—
Missense Z
—
LOEUF
Clinical Summary— FAM85B
📋
ClinVar Variants
40 Pathogenic / Likely Pathogenic of 93 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

93 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic39
Likely Pathogenic1
Likely Benign1
Benign51
Conflicting1
39
Pathogenic
1
Likely Pathogenic
1
Likely Benign
51
Benign
1
Conflicting

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————39
Likely Pathogenic
————1
VUS
————0
Likely Benign
————1
Benign
————51
Conflicting
—1
Total—93

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

FAM85B · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 5 full-text resultsSearch PubTator3 ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Top 5 resultsSearch Europe PMC ↗

External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients